PAF: Opioid Epidemic

In this report, we evaluated interventions to combat the growing opioid epidemic in the United States. We developed a methodology for evaluating interventions based on 3 key criteria: evidence, cost-effectiveness, and scalability. We also created a scoring rubric to simplify our conclusions on the strength of the interventions in each of these 3 areas. We looked at interventions in 5 broad problem areas: pain treatment, opioid supply, addiction treatment, access/referral to treatment, and harm reduction.

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Josh Greene

Joshua Greene is a professor in the Harvard Department of Psychology where he runs the Moral Cognition Lab. He received his bachelor’s degree from Harvard and then a PhD in philosophy at Princeton where he was mentored by many bright lights of analytical philosophy, including Peter Singer, who served on his committee. After doing a post-doc in a a cognitive neuroscience lab, Greene returned to Harvard to begin his own lab, the Moral Cognition Lab, which studies both descriptive and normative psychology and philosophy.

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PAF: Climate Change

We analyzed climate change from a high-level perspective, exploring various potential philanthropic interventions: Direct emissions reductions, adaptation, R&D,  advocacy/litigation, and climate finance. We recommend fighting coal power in asia, building capacity in the US at local levels, and investing in innovative climate finance models.  

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PAF: Scientific Reproducibility

In this report, we considered four broad interventions: post-publication peer review, quantitative metrics for transparency (e.g. “transparency index”), tenure criteria, and characterizing dependency relationships between pieces of research. All of these categories can be implemented in different ways, and can improve reproducibility through multiple channels.

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PAF: Mental Health in Sub-Saharan Africa

Although traditionally mental health has not been considered an immediate cause for concern in Sub-Saharan Africa, it is increasingly receiving more attention as the extent in which people suffer from various disorders has become apparent. Within this report, our team seeks to quantify and analyze the burden of mental health disorders in the region, estimate the cost-effectiveness of various interventions, recommend local organizations that are taking a scientifically-sound, scalable approach, and recommend promising research opportunities to develop new, highly cost-effective and scalable interventions.

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